High coverage genome sequencing and identification of genomic variants in Bengal tiger (Panthera tigris tigris)

11 May in de novo genome sequencing, Genome Assembly, Sequencing

India's renowned genomics and bioinformatics company Nucleome Informatics, annouces the succesful completion of Indian Bengal tiger genome sequencing in collaboration with LaCONES, CCMB, Hyderabad. Panthera tigris tigris, one of six extant tiger subspecies, occurs solely in the Indian subcontinent. Although endangered and threatened by various extinction...

Deep sequencing of small RNAs reveals ribosomal origin of microRNAs in Oryza sativa and their regulatory role in high temperature

04 May in miRNA Sequencing

MicroRNAs are small noncoding regulatory RNAs which control gene expression by mRNA degradation or translational repression. They are significant molecular players regulating important biological processes such as developmental timing and stress response. We report here the discovery of miRNAs derived from ribosomal DNA using the...

RNA sequencing of murine mammary epithelial stem-like cells (HC11) undergoing lactogenic differentiation and its comparison with embryonic stem cells

11 April in RNA Sequencing

Understanding of transcriptional networks specifying HC11 murine mammary epithelial stem cell-like cells (MEC) in comparison with embryonic stem cells (ESCs) and their rewiring, under the influence of glucocorticoids (GC) and prolactin (PRL) hormones, is critical for elucidating the mechanism of lactogenesis. In this data note,...