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Nucleome: a deep-tech genomics enterprise

Visit the 'Contact us' page to share your project requirement. Thank you.

Empowering Precision Genomics for a Healthier Future

Genomics

Nucleome Informatics offers de novo genome sequencing, resequencing, and targeted resequencing for variant detection. Our clinical genetic testing identifies pathogenic markers for diagnosis and personalized treatment. Using next-generation sequencing and bioinformatics, we deliver actionable genomic insights for researchers, clinicians, and biotech innovators.

Epigenomics

Nucleome Informatics provides ChIP-Seq, WGBS, methylation arrays, and PacBio HiFi sequencing for epigenetic analysis. We profile protein-DNA interactions, DNA methylation, and chromatin accessibility. Our bioinformatics solutions deliver insights into gene regulation, disease mechanisms, and epigenetic inheritance for health and environmental research.

Metagenomics

Nucleome Informatics offers Shotgun metagenome, 16S rRNA, fungal ITS, and metatranscriptome sequencing using PacBio HiFi and Illumina. We profile microbial communities, generate metagenome assembled genomes, and study epigenetic modifications, supporting clinical and environmental research with detailed microbial diversity insights.

Transcriptomics

Nucleome Informatics sequences Total RNA, mRNA, lncRNA, and miRNA, using Iso-Seq and single-cell RNA sequencing. We characterize isoforms, gene expression, and cellular heterogeneity. Our bioinformatics supports discoveries in health, agriculture, and environmental genomics with precise transcriptomic insights.

Advanced Long Read Genomics

Nucleome Informatics, South Asia’s first PacBio Sequel II and Revio service provider, offers high-throughput HiFi sequencing for genome assembly, variant detection, and epigenetic profiling. Our services include PureTarget panels, Kinnex transcriptomes, and 16S rRNA analysis, delivering comprehensive genomic insights with expert bioinformatics.

Bioinformatics

Nucleome Informatics provides bioinformatics for genomics, analyzing sequencing data for variant detection, transcriptomics, metagenomics, and epigenomics. Using AI and ML, we deliver clinical reporting and actionable insights for oncology, rare diseases, agriculture, and environmental health, empowering precision medicine and research.

Service Verticals

DrPAM- Plant, Animal and Microbial Genomics

DrPAM – Plant, Animal & Microbial Genomics
Harnessing genomics to accelerate discoveries in agriculture, livestock, and microbiome research.
Specialized in trait discovery, pathogen resistance, microbial diversity, and ecosystem health.
Providing sequencing, bioinformatics, and AI-driven insights for sustainable innovation.

DrSeq-Human Genomics and Genetic testing

DrSeq is a clinical genomics lab by Nucleome Informatics. We offer a wide range of services in human genome sequencing, clinical exome sequencing, pharmacogenomics, rare diseases, reproductive health, eye disorders and more.

DrSeed-Agricultural Genomics

DrSeed – AgriGenomics for Seed Industry
Enabling seed companies and agri-scientists to accelerate breeding with genomic selection tools.
Supporting the discovery of resilient, high-yield, and climate-smart crop varieties.
Integrating genomics, data science, and AI to unlock next-generation seed innovation.

About Our Company

Nucleome Informatics Pvt. Ltd. is a pioneering genomics company dedicated to discovery, innovation, and product development. Headquartered in Hyderabad, we are building one of India’s most advanced genomics ecosystems by combining high-resolution sequencing, multi-omics, advanced bioinformatics, and AI-driven analytics to decode genomes and deliver transformative applications.

Our vision is to place India at the forefront of the genomics revolution, while our mission is to harness the power of genomes to improve healthcare, strengthen agriculture, and advance scientific discovery.

We operate through three specialized verticals:

DrSeq – our human genomics vertical focused on healthcare and clinical NGS, developing solutions for early cancer detection, rare disease diagnostics, therapy selection, and precision medicine.
DrSeed – our agricultural genomics platform supporting the seed industry through molecular breeding, trait discovery, genomic selection, and development of climate-resilient crops.
DrPAM – our academic genomics and research vertical providing advanced genomics infrastructure, AI-powered bioinformatics, and collaborative solutions to enable large-scale discovery in life sciences.

By integrating genomics technologies with AI-powered data interpretation, Nucleome delivers actionable insights across oncology, rare diseases, agriculture, and biodiversity conservation. Our approach enables complex variant detection, population genomics, and predictive analytics at a scale unmatched in the region.

As a recognized leader, we partner with national initiatives, global consortia, academic institutions, and industry innovators to drive impactful collaborations. Looking ahead, we are expanding AI-driven clinical solutions, building large population reference datasets, and accelerating translational genomics for healthcare, agriculture, and research.

At our core, we believe the future of science and society is written in genomes. At Nucleome Informatics, we are decoding them—empowering discovery, innovation, and sustainable solutions for generations to come.

Innovation Spotlight

DrSeq Precision Medicine and Pharmacogenomics testing
06 November, 2025 in Uncategorized No comment
The 4 Power Biomarkers WGS-HiFi Test for Cancer
14 October, 2025 in Uncategorized No comment
Understanding Genomic Testing: WES vs. WGS with HiFi Technology
08 October, 2025 in genome resequencing PacBio Sequencing Variant Analysis No comment

Thank for providing us with good quality PacBio Reads. I am highly satisfied with the quality of services, sequence reads and read length. I am looking forward to get many more such sequencing services from your company
Dr. Arun Kumar KP, Staff Scientist & Head, Laboratory of Molecular Genetics, CDFD
I had a very fruitful discussion regarding the project, and very detailed analysis of complete pipeline, as well as the protocols, were discussed. The team of Nucleome Informatics gave me very useful insights on the data and different ways of analysis from our side. We have given inputs to do further analysis. The feedback regarding the quality of the data is very encouraging. I am very excited by the chromosome-wise distribution of the data.
Dr. Bhavani Shankar, Head Immunology Section
I would like to appreciate the help we got from the entire team of Nucleome Informatics for our project. Being a new explorer in the NGS field, we were not very familiar with the area/work, but Team Nucleome was quite helpful in not only our field of interest but guided us to explore various associated fields.Thank you very much to Mr Dushyant and his team.
Dr. Vipul Kr Reddy, Scientific Officer, BARC