We offer a broad spectrum of genomics services. We provide de novo genome sequencing, genome resequencing, exome sequencing, optical mapping, single cell DNA sequencing, etc. on different next generation technologies like Illumina HiSeq 2500, NovaSeq 6000, Pacific Biosciences PacBio RS II, Sequel II and Bionano Saphyr System. We have sequenced many plants and microbial de novo genomes and regularly working on sequencing of cancer genomes and human exomes.

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For clients working in epigenomics studies, we can offer ChIP Sequencing and Whole genome Bisulfite Sequencing services. The client can use these services to investigate methylation patterns quantitatively across the genome using sequencing- and array-based techniques and gain insight into protein and DNA interactions. The client can discover the potential impact of chromatin modifications and local structural changes in gene expression.

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Nucleome Informatics is a well-known service provider of Shotgun metagenome sequencing, full length 16s Amplicon sequencing (V1 to V9) & metatranscriptome sequencing. We also provide denovo and resequencing of microbial genomes on PacBio Sequel II and NovaSeq 6000. The client can use environmental genomics service to profile entire microbial communities from complex samples, discover novel organisms, and explore the dynamic nature of microbial populations under changing environmental conditions.

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Nucleome Informatics is a leading Transcriptome sequencing or RNA Sequencing (RNA-Seq) service provider in India. We can sequence Total RNA, Long non-coding RNA, mRNA and Small RNA/miRNA from all organisms to discover novel genes, understanding host-pathogen immune interactions, quantifying gene expression changes, and tracking disease progression. We can isolate RNA from tissue or single cell to study single cell RNA sequencing.

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PacBio Sequel II Services

Nucleome is South Asia's first company to offer PacBio Sequel II services. Our sequencing laboratory is based in Hyderabad, India. We are currently offering whole genome sequencing, ISO Sequencing, metagenome sequencing and variant discovery services on Sequel II platform. We also have HMW gDNA preparation service for clients who wish to transfer tissue samples. Our data analysis team is experienced in developing high quality assemblies using PacBio Sequel II data. Scaffolding and Super Scaffolding with Optical Map and HiC data are also available.

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We have entire spectrum of NGS data analysis like de novo genome assembly, genome annotation, variant calling, denovo transcriptome analysis, reference based RNA seq analysis, small RNA seq data analysis, metagenome analysis, 16s amplicon seq analysis, chip seq analysis, WGBS analysis, etc. You can choose standard or advanced analysis based on your project requirements and budget. Our qualified NGS scientists can help clients in the design and successful execution of projects.

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Big Data Decoder
Big Data decoder is Next Generation Sequencing Server especially designed for customers decoding the big data of genes and genomes. Invest now in a Big Data Decoder to publish the smarter NGS results faster.
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DrSeq Software
Upload the data, choose the parameters, press submit button and drink a cup of coffee while DrSeq analyses your RNA seq datasets. The easiest way to learn, customise and analyse RNA seq datasets.
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About Our Company

Nucleome Informatics is the fastest growing next generation sequencing and bioinformatics service provider in India with many academic and industrial customers worldwide. Nucleome is India’s first and only genomics company to provide services on PacBio Sequel II platform. Company is very well regarded for its expertise in de novo genome sequencing of larger genomes using hybrid assembly approach using PacBio Sequel 2, 10x genomics, optical mapping and Hi-C data. We offer ISO Seq service on PacBio Sequel 2 to annotate the newly assembled genomes, discover novel genes, isofroms, transcripts and perform differential gene expression as well. Transcriptome sequencing (coding and non-coding RNA Sequencing) and genome resequencing services on HiSeq 2500 (SBS V4 Chemistry) and NovaSeq 6000 are frequently being used by our customers. Nucleome Informatics offers whole human genome sequencing and exome sequencing in India for researchers and Physicians who are interested in sequencing Patient’s genome/exome to mine SNPs, CNVs or SVs. Nucleome is among very few companies in the world to offer cfDNA Sequencing and Cell line genome sequencing services. For our efforts in genomics research, we are awarded as ‘The 10 Most Recommended Pharma & Life Sciences Solution providers in 2019’ by Insights Success Magzine.

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