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Genomics, Genotyping, Bioinformatics

Visit the 'Contact us' page to share your project requirement. Thank you.

Next Generation Sequencing and Analysis Services

Genomics

Nucleome Informatics is India's leading genomics service provider. We provide de novo genome sequencing, genome resequencing, exome sequencing, optical mapping, single cell DNA sequencing, etc. on multiple next generation technologies like NovaSeq 6000, PacBio Sequel II and Bionano Saphyr System. We have sequenced many plants and microbial de novo genomes and regularly working on sequencing of cancer genomes and human exomes.

Epigenomics

For clients working in epigenomics studies, we can offer ChIP Sequencing and Whole genome Bisulfite Sequencing services. The client can use these services to investigate methylation patterns quantitatively across the genome using sequencing- and array-based techniques and gain insight into protein and DNA interactions. The client can discover the potential impact of chromatin modifications and local structural changes in gene expression.

Metagenomics

Nucleome Informatics is a well-known service provider of Shotgun metagenome sequencing, full length 16s Amplicon sequencing (V1 to V9) & metatranscriptome sequencing. We also provide denovo and resequencing of microbial genomes on PacBio Sequel II and NovaSeq 6000. The client can use environmental genomics service to profile entire microbial communities from complex samples, discover novel organisms, and explore the dynamic nature of microbial populations under changing environmental conditions.

Transcriptomics

Nucleome Informatics is a leading Transcriptome sequencing or RNA Sequencing (RNA-Seq) service provider in India. We can sequence Total RNA, Long non-coding RNA, mRNA and Small RNA/miRNA from all organisms to discover novel genes, understanding host-pathogen immune interactions, quantifying gene expression changes, and tracking disease progression. We can isolate RNA from tissue or single cell to study single cell RNA sequencing.

PacBio Sequel II Services

Nucleome is South Asia's first company to offer PacBio Sequel II services. Our sequencing laboratory is based in Hyderabad, India. We are currently offering whole genome sequencing, ISO Sequencing, metagenome sequencing and variant discovery services on Sequel II platform. We also have HMW gDNA preparation service for clients who wish to transfer tissue samples. Our data analysis team is experienced in developing high quality assemblies using PacBio Sequel II data. Scaffolding and Super Scaffolding with Optical Map and HiC data are also available.

BioIT

We have entire spectrum of NGS data analysis like de novo genome assembly, genome annotation, variant calling, denovo transcriptome analysis, reference based RNA seq analysis, small RNA seq data analysis, metagenome analysis, 16s amplicon seq analysis, chip seq analysis, WGBS analysis, etc. You can choose standard or advanced analysis based on your project requirements and budget. Our qualified NGS scientists can help clients in the design and successful execution of projects.

Targeted Panels and Genotyping

BigData Decoder SNP Genotyping

The BigData decoder is the range of Genotyping solutions specially designed for customers decoding the big SNP data of genes and genomes. Invest now in a Big Data Decoder solution to execute the smarter Genotyping results faster.

DrSeq Human Genomics Panels

DrSeq is a clinical genomics lab by Nucleome Informatics. We offer a wide range of services in human genome sequencing, clinical exome sequencing, pharmacogenomics, rare diseases, reproductive health, eye disorders and more.

About Our Company

Nucleome Informatics is a pioneering leader in Next-Generation Sequencing (NGS), bioinformatics, and genomics services, with a strong focus on advancing healthcare, biodiversity research, and agricultural genomics. With over 12 years of experience, Nucleome leverages cutting-edge genomic technologies, bioinformatics, and artificial intelligence (AI) to drive transformative innovations in precision medicine, genetic research, and data-driven research programs.

Our expertise spans diverse areas, including:

Human Genomics: As India’s first and only genomics company to offer services on the PacBio Sequel II platform, Nucleome has earned global recognition for its capabilities in de novo genome sequencing, whole genome sequencing (WGS), whole exome sequencing (WES), targeted oncology panels, reproductive health testing, and genetic disease diagnostics. Visit DrSeq webpage to know more about our clinical genomics services.

Plant Genomics: Revolutionizing crop research through genome sequencing, genetic trait discovery, and genomic-assisted breeding to enhance crop yield, disease resistance, and environmental resilience.

Microbial Genomics: Pioneering microbial genome sequencing to understand complex microbiomes, microbial diversity, and its applications in agriculture, biotechnology, and human health.

Animal Genomics: Supporting genetic improvement programs in livestock and genetic disease detection in companion animals through advanced sequencing technologies and AI-driven analyses.

Genotyping and AI-Driven Breeding: Implementing genotyping efforts that support AI-powered breeding and genomic data-driven breeding programs to accelerate agricultural innovation and optimize traits in crops and livestock.

New Gene Discovery and Characterization: Identifying and characterizing novel genes with applications in crop improvement, disease resistance, and biotechnology advancements.

Genome-Edited Product Characterization: Offering solutions for the characterization of genome-edited products to ensure precision and safety in CRISPR/Cas9-based research and other genome editing technologies.

Academic Research Support: Providing vital genomics services to agricultural scientists, enabling data-driven research in areas such as plant breeding, genetic resource conservation, and climate change adaptation.

Events and publications

Arunanchali Yak Genome Sequenced
16 May, 2025 in de novo genome sequencing No comment
PAG Asia (India) 2025: Workshop on Genome Assembly on 18th March 2025
19 February, 2025 in Genome Assembly Sequencing Webinar No comment

Thank for providing us with good quality PacBio Reads. I am highly satisfied with the quality of services, sequence reads and read length. I am looking forward to get many more such sequencing services from your company
Dr. Arun Kumar KP, Staff Scientist & Head, Laboratory of Molecular Genetics, CDFD
I had a very fruitful discussion regarding the project, and very detailed analysis of complete pipeline, as well as the protocols, were discussed. The team of Nucleome Informatics gave me very useful insights on the data and different ways of analysis from our side. We have given inputs to do further analysis. The feedback regarding the quality of the data is very encouraging. I am very excited by the chromosome-wise distribution of the data.
Dr. Bhavani Shankar, Head Immunology Section
I would like to appreciate the help we got from the entire team of Nucleome Informatics for our project. Being a new explorer in the NGS field, we were not very familiar with the area/work, but Team Nucleome was quite helpful in not only our field of interest but guided us to explore various associated fields.Thank you very much to Mr Dushyant and his team.
Dr. Vipul Kr Reddy, Scientific Officer, BARC