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Services offered by Nucleome and DrSeq Labs:

Welcome to Nucleome Informatics, your premier genomics service provider based in India. At Nucleome, we specialize in offering cutting-edge genomics solutions across various domains including Plant Genomics, Microbial Genomics, Animal and Wildlife Genomics, and Human Genomics. With a focus on leveraging advanced technologies and expertise, we are committed to delivering accurate, reliable, and comprehensive genomic services to meet the diverse needs of our clients.

Focus Areas:

  1. Plant Genomics:
    • De Novo Genome Assembly: Nucleome specializes in building de novo genomes of plant species that have not yet been sequenced, facilitating genetic studies and breeding programs.
    • Resequencing for Marker Discovery: Our resequencing services enable the identification of genetic markers associated with important traits, aiding in crop improvement and biodiversity conservation.
    • Custom SNP Chip Development: We offer customized SNP chip development for high-throughput genotyping, empowering precision breeding and genomic selection in plants.
    • SSR Sequencing: Nucleome conducts SSR (Simple Sequence Repeat) sequencing for population structure analysis and genetic diversity studies in plant populations.
    • RNA Sequencing (RNA-Seq): Our RNA-Seq services enable comprehensive transcriptomic analysis, elucidating gene expression patterns, alternative splicing events, and regulatory mechanisms in diverse biological systems.
  2. Microbial Genomics:
    • Microbiome Array for Pathogen Detection: Our microbiome array platform allows for rapid and comprehensive detection of pathogens in microbial communities, enabling early disease diagnosis and one health research management.
    • Whole Genome Sequencing: Nucleome offers whole genome sequencing services for microbial pathogens, facilitating epidemiological studies, strain typing, and antimicrobial resistance analysis.
    • Metagenome Sequencing: We provide metagenome sequencing services to explore microbial communities in diverse environments, offering insights into ecosystem functioning, microbial diversity, and biotechnological applications.
    • MAGs (Metagenome-Assembled Genomes): Nucleome specializes in the reconstruction and analysis of MAGs from complex metagenomic datasets, enabling the characterization of novel microbial species and functions.
    • Full-Length 16S Amplicon Sequencing: Using HiFi sequencing technology from PacBio, Nucleome performs full-length 16S amplicon sequencing for species-level identification and taxonomic profiling of microbial communities with unparalleled accuracy and resolution.
  3. Animal and Wildlife Genomics:
    • De Novo Genome Assembly: We specialize in de novo genome assembly of non-model animal species, supporting conservation efforts, population genetics, and evolutionary studies.
    • Resequencing for Marker Discovery: Our resequencing services aid in the discovery of genetic markers associated with traits of interest, facilitating wildlife management and conservation breeding programs.
    • Custom SNP Chip Development: Nucleome develops custom SNP chips for genotyping wildlife populations, enabling population genetic analyses and GWAS studies.
    • SSR Sequencing: Nucleome conducts SSR (Simple Sequence Repeat) sequencing for population structure analysis and genetic diversity studies in wildlife/animal populations.
  4. Human Genomics: Visit Nucleome’s Human Genomics lab DrSeq at  www.DrSeq.com for more information.
    • Whole Genome and Exome sequencing
    • Targeted panels for genetic disorders
    • Genome-Wide Association Studies (GWAS): We conduct GWAS studies to identify genetic variants associated with complex traits and diseases, offering insights into disease mechanisms and personalized medicine.
    • SNP Genotyping: Nucleome provides high-throughput SNP genotyping services for population genetics, ancestry studies, and pharmacogenomics research.
    • Personalized Genomics: Nucleome offers personalized genomics services for precision medicine applications, including genetic risk assessment, disease predisposition testing, and therapeutic target identification.
    • Pharmacogenomics: Our pharmacogenomics services enable the identification of genetic variants affecting drug response and toxicity, informing personalized treatment strategies and improving medication efficacy and safety.
    • RNA Sequencing (RNA-Seq): Our RNA-Seq services enable comprehensive transcriptomic analysis, elucidating gene expression patterns, alternative splicing events, and regulatory mechanisms in diverse biological systems.
    • ISO-Seq (Isoform Sequencing): Nucleome offers ISO-Seq services for full-length transcript sequencing, facilitating the discovery and characterization of novel transcript isoforms and splice variants.
    • Epigenome Profiling: We provide epigenome sequencing services to investigate DNA methylation, histone modifications, and chromatin accessibility, offering insights into gene regulation, development, and disease.

Our Services:

  1. NGS (Next-Generation Sequencing): Nucleome offers state-of-the-art Next-Generation Sequencing services, providing high-throughput sequencing solutions tailored to your specific requirements. Whether exploring the complexities of plant genomes, studying microbial diversity, investigating animal genetics, or delving into human genomics, our NGS platforms deliver unparalleled depth and breadth of sequencing data.
  2. Long Reads Sequencing by PacBio: Unravel the intricacies of genomes with our PacBio long reads sequencing technology. With its ability to generate long, continuous reads, PacBio sequencing offers invaluable insights into complex genomic regions, structural variations, and epigenetic modifications. Nucleome’s expertise in PacBio sequencing ensures accurate assembly and annotation of genomes across diverse organisms.
  3. Genotyping: Nucleome provides precise genotyping services for various applications, including marker-assisted breeding, population genetics, and association studies. Utilizing advanced genotyping platforms and methodologies, we deliver accurate genotype data with high throughput and efficiency, enabling robust genetic analysis and selection strategies.
  4. Bioinformatics Data Analysis: Our comprehensive bioinformatics expertise complements our sequencing services, offering in-depth analysis and interpretation of genomic data. From quality control and alignment to variant calling functional annotation, and pathway analysis, our bioinformatics pipelines are customized to extract meaningful insights from complex genomic datasets. Whether you require basic data processing or advanced genomic analysis, our bioinformatics solutions are tailored to meet your specific research goals.

Why Choose Nucleome Informatics?

  • Expertise: Our team of experienced scientists and bioinformaticians brings extensive expertise in genomics and data analysis, ensuring the highest standards of quality and accuracy in every project.
  • State-of-the-Art Infrastructure: Nucleome is equipped with state-of-the-art sequencing platforms, bioinformatics tools, and computational resources, enabling us to deliver superior genomics solutions with fast turnaround times.
  • Customized Solutions: We offer flexible and customizable services tailored to your research objectives, budget, and timelines.
  • Collaborative Approach: We believe in fostering collaborative partnerships with our clients, providing ongoing support and guidance at every project stage to ensure success.

Partner with Nucleome Informatics for your sector-specific genomics needs and unlock the potential of your research. Contact us today to learn more about our services and how we can assist you in achieving your genomic goals.